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Article

Individualized treatment with voriconazole in the Chinese population: Inflammation level as a novel marker for dose optimization.

British journal of clinical pharmacology - 1 Feb 2024

Hao Xu, Li Yuanyuan, Zhang Ying, Bian Jialu, Zhao Jinxia, Zhao Yinyu, Hu Lei, Luo Xingxian, Yang Changqing, Feng Yufei, Huang Lin

Abstract excerpt

AIMS: The aim of this study was to explore the influence and possible mechanisms of pharmacokinetics-related gene polymorphisms, especially CYP2C19 polymorphisms, and non-genetic factors combined with the inflammatory status on the voriconazole (VRC) metabolism of the Chinese population. METHODS: Clinical studies were performed by collecting more than one VRC trough concentration and C-reactive protein (CRP)...

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Identifiers

PMID: 37766511
DOI: 10.1111/bcp.15916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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