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Article

RBMX involves in telomere stability maintenance by regulating TERRA expression

27 Sept 2023

Abstract excerpt

Telomeric repeat-containing RNA (TERRA) is a class of long noncoding RNAs (lncRNAs) that are transcribed from subtelomeric to telomeric region of chromosome ends. TERRA is prone to form R-loop structures at telomeres by invading into telomeric DNA. Excessive telomere R-loops result in telomere instability, so the TERRA level needs to be delicately modulated. However, the molecular mechanisms and factors...

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PMID: 37756323
DOI: 10.1371/journal.pgen.1010937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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RBMX involves in telomere stability maintenance by regulating TERRA expressionPMID 37756323Read ↗

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The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loopsSemantic proximity Read ↗

TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signalingSemantic proximity Read ↗

R-Loops at Chromosome Ends: From Formation, Regulation, and Cellular ConsequenceSemantic proximity Read ↗

BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.Semantic proximity Read ↗

TElomeric repeat-containing RNA (TERRA): Physiological functions and relevance in cancerSemantic proximity Read ↗

In Vitro Characterization of the Physical Interactions between the Long Noncoding RNA TERRA and the Telomeric Proteins TRF1 and TRF2Semantic proximity Read ↗

TERRA stability is regulated by RALY and polyadenylation in a telomere-specific mannerSemantic proximity Read ↗

RTEL1 Influences the Abundance and Localization of TERRA RNASemantic proximity Read ↗

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