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Article

Recent Advances in the Development of HIV-1 Vaccines Using Replication-Incompetent Adenovirus Vectors

27 Jan 2004

Abstract excerpt

An increasing body of evidence suggests that a vaccine that elicits anti-HIV-1 cellular immunity could provide the basis for an effective AIDS vaccine. Comparative immunization experiments testing a variety of vaccine approaches have demonstrated that replication-incompetent adenovirus vectors are an effective means for eliciting cytotoxic T-lymphocyte (CTL) immune responses against HIV-1 antigens. These immune...

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PMID: 14746526
DOI: 10.1146/annurev.med.55.091902.104344

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