Article
RORB, an Alzheimer's disease susceptibility gene, is associated with viral encephalitis, an Alzheimer's disease risk factor.
Clinical neurology and neurosurgery - 1 Oct 2023
Lehrer Steven, Rheinstein Peter H
Abstract excerpt
BACKGROUND: Viral encephalitis increases later-life risk of Alzheimer's disease (AD) by a factor of 31. METHODS: To further evaluate this finding, we examined the relationship of West Nile virus (WNV) to Alzheimer's disease in 50 US states. In addition, we performed a genome wide association study (GWAS) of viral encephalitis cases in UK Biobank (UKBB) to see if encephalitis genes might be related to AD. RESULTS:...
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