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Article

Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.

Alzheimer's research & therapy - 24 Sept 2021

Huang Shu-Yi, Yang Yu-Xiang, Kuo Kevin, Li Hong-Qi, Shen Xue-Ning, Chen Shi-Dong, Cui Mei, Tan Lan, Dong Qiang, Yu Jin-Tai

Abstract excerpt

BACKGROUND: Observational studies have suggested that herpesvirus infection increased the risk of Alzheimer's disease (AD), but it is unclear whether the association is causal. The aim of the present study is to evaluate the causal relationship between four herpesvirus infections and AD. METHODS: We performed a two-sample Mendelian randomization analysis to investigate association of four active herpesvirus...

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Identifiers

PMID: 34560893
DOI: 10.1186/s13195-021-00905-5
PMCID: PMC8464096

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