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Article

Brain molecular mechanisms in Rasmussen encephalitis

7 Nov 2022

Abstract excerpt

Abstract Objective This study was undertaken to identify molecular mechanisms in brain tissue of Rasmussen encephalitis (RE) when compared to people with non‐RE epilepsy (PWE) and control cases using whole exome sequencing (WES), RNAseq, and proteomics. Methods Frozen brain tissue (ages = 2–19 years) was obtained from control autopsy (n = 14), surgical PWE (n = 10), and surgical RE cases (n = 27). We evaluated...

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PMID: 36336987
DOI: 10.1111/epi.17457

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