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Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis

28 Sept 2021

Abstract excerpt

Background and Objectives To investigate the genetic determinants of the most common type of antibody-mediated autoimmune encephalitis, anti-NMDA receptor (anti-NMDAR) encephalitis. Methods We performed a genome-wide association study in 178 patients with anti-NMDAR encephalitis and 590 healthy controls, followed by a colocalization analysis to identify putatively causal genes. Results We identified 2 independent...

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PMID: 34584012
DOI: 10.1212/nxi.0000000000001085

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