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Article

Prognostic and Pharmacotypic Heterogeneity of Hyperdiploidy in Childhood ALL

20 Sept 2023

Abstract excerpt

PURPOSE: High hyperdiploidy, the largest and favorable subtype of childhood ALL, exhibits significant biological and prognostic heterogeneity. However, factors contributing to the varied treatment response and the optimal definition of hyperdiploidy remain uncertain. METHODS: We analyzed outcomes of patients treated on two consecutive frontline ALL protocols, using six different definitions of hyperdiploidy:...

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PMID: 37729596
DOI: 10.1200/jco.23.00880

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