Article
The fruit fly acetyltransferase chameau promotes starvation resilience at the expense of longevity.
EMBO reports - 9 Oct 2023
Venkatasubramani Anuroop Venkateswaran, Ichinose Toshiharu, Kanno Mai, Forne Ignasi, Tanimoto Hiromu, Peleg Shahaf, Imhof Axel
Abstract excerpt
Proteins involved in cellular metabolism and molecular regulation can extend lifespan of various organisms in the laboratory. However, any improvement in aging would only provide an evolutionary benefit if the organisms were able to survive under non-ideal conditions. We have previously shown that Drosophila melanogaster carrying a loss-of-function allele of the acetyltransferase chameau (chm) has an increased...
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