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Article

Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a.

Scientific reports - 4 Aug 2017

An Phan Nguyen Thuy, Shimaji Kouhei, Tanaka Ryo, Yoshida Hideki, Kimura Hiroshi, Fukusaki Eiichiro, Yamaguchi Masamitsu

Abstract excerpt

Epigenetics is now emerging as a key regulation in response to various stresses. We herein identified the Drosophila histone methyltransferase G9a (dG9a) as a key factor to acquire tolerance to starvation stress. The depletion of dG9a led to high sensitivity to starvation stress in adult flies, while its overexpression induced starvation stress resistance. The catalytic domain of dG9a was not required for...

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Identifiers

PMID: 28779125
DOI: 10.1038/s41598-017-07566-1
PMCID: PMC5544687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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