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Article

Correlations between Multiple SNPs and HbF Levels in β-Thalassemia Carriers.

Clinical laboratory - 1 Sept 2023

Xu Qin, Huang Ling, Jin Tingting, Han Yuanyuan, Liu Juan, Zhang Wenqiu, Biao Yao, An Bangquan, Huang Shengwen

Abstract excerpt

BACKGROUND: Increased hemoglobin F (HbF) expression in individuals with β-thalassemia contributes to the alleviation of pathological phenomena and the reduction of mortality. We have investigated the correlation between six single nucleotide polymorphisms (SNPs) in BCL11A, XmnI-HBG2, HBS1L-MYB, and ANTXR1 and the levels of HbF in β-thalassemia carriers. METHODS: Samples were collected from 330 cases of...

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PMID: 37702677
DOI: 10.7754/Clin.Lab.2023.230220

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