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Article

Genetic polymorphism of SNPs rs9399137 and rs4895441in HBS1L-MYB and SNP rs766432 in BCL11A among β-thalassemia Egyptian patients.

BMC genomic data - 3 Jun 2026

Abdelrahman Abdelrahman A, Talaat Randa M, El-Halfawy Ibrahim Abdo, Alalwi Mohamed Ramzy, Rizk Dina Malak Yousef

Abstract excerpt

BACKGROUND: This study aimed to evaluate the role of two genetic polymorphisms (rs9399137 and rs4895441) in the HBS1L-MYB and rs766432 of BCL11A genes as determinant HbF level and disease severity in Egyptian β-thalassemia patients. METHODS: Blood samples were obtained from 100 participants, comprising 50 individuals with β-thalassemia and 50 healthy controls. Hematological assessment was conducted through...

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Identifiers

PMID: 42237232
DOI: 10.1186/s12863-026-01436-4
PMCID: PMC13235190

Genes

MYB
BCL11A
HBS1L

Provenance

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