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Article

CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Voriconazole in Chinese Kidney Transplant Patients.

The Annals of pharmacotherapy - 1 Jun 2024

Zhang Yundi, Du Yue, Ren Shuyu, Li Yue, Zhang Xiaoming, Cao Xiaohong, Liu Fengxi, Zong Huiying, Li Yan

Abstract excerpt

BACKGROUND: The effect of drug-drug interaction (DDI) between tacrolimus and voriconazole on the pharmacokinetics of tacrolimus in different CYP3A5 genotypes has not been reported in previous studies. OBJECTIVE: The objective of this study was to investigate whether CYP3A5 genotype could influence tacrolimus-voriconazole DDI in Chinese kidney transplant patients. METHODS: All kidney transplant patients were...

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Source

Identifiers

PMID: 37702380
DOI: 10.1177/10600280231197399

Genes

CYP3A5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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