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Article

Cigarette Smoking and Intracranial Aneurysms: A Pilot Analysis of SNPs in the CYP2A6 Gene in the Italian Population.

World neurosurgery - 1 Nov 2023

Ferrari Erika, Cornali Claudio, Fiorindi Alessandro, Agosti Edoardo, Gallone Salvatore, Rubino Elisa, Ponzio Francesco, Fontanella Marco Maria, De Maria Lucio

Abstract excerpt

BACKGROUND: Cigarette smoking is a modifiable risk factor associated with formation and rupture of intracranial aneurysms (IAs). Cytochrome P450 2A6 (CYP2A6) is the main enzyme implied in catabolism of nicotine and xenobiotics, giving rise to oxidative stress products. Our study investigated the associations between specific single-nucleotide polymorphisms (SNPs) in the CYP2A6 gene and the presence of sporadic...

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Identifiers

PMID: 37689358
DOI: 10.1016/j.wneu.2023.08.128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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