Aldosterone synthase gene (CYP11B2) -344C/T polymorphism contributes to the risk of recurrent cerebral ischemia.

doi:10.1089/gtmb.2013.0026

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Article

Aldosterone synthase gene (CYP11B2) -344C/T polymorphism contributes to the risk of recurrent cerebral ischemia.

Genetic testing and molecular biomarkers - 1 Jul 2013

Ji Peng, Jiang Limin, Zhang Shuling, Cui Wei, Zhang Daopei, Fu Shengqi, Zhang Hongtao

Abstract excerpt

BACKGROUND: Accumulating evidence suggests that CYP11B2 rs1799998 (-344C/T) polymorphism is independently associated with an increased risk of stroke. Our aim was to determine whether -344C/T also predisposes to recurrent cerebral ischemia following in patients with symptomatic intracranial atherosclerosis disease (ICAD). METHODS: Genotypes of the CYP11B2 -344C/T polymorphism were determined by polymerase chain...

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PMID: 23701507
DOI: 10.1089/gtmb.2013.0026

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