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Article

Comparison of Tumour-Specific Phenotypes in Human Primary and Expandable Pancreatic Cancer Cell Lines.

International journal of molecular sciences - 31 Aug 2023

Guo Feng, Kan Kejia, Rückert Felix, Rückert Wolfgang, Li Lin, Eberhard Johannes, May Tobias, Sticht Carsten, Dirks Wilhelm G, Reißfelder Christoph, Pallavi Prama, Keese Michael

Abstract excerpt

There is an ongoing need for patient-specific chemotherapy for pancreatic cancer. Tumour cells isolated from human tissues can be used to predict patients' response to chemotherapy. However, the isolation and maintenance of pancreatic cancer cells is challenging because these cells become highly vulnerable after losing the tumour microenvironment. Therefore, we investigated whether the cells retained their...

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Identifiers

PMID: 37686338
DOI: 10.3390/ijms241713530
PMCID: PMC10488093

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