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Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation

22 Jul 2015

Abstract excerpt

Pancreatic cancer stem cells (CSCs) have been first described in 2007 and since then have emerged as an intriguing entity of cancer cells with distinct functional features including self-renewal and exclusive in vivo tumorigenicity. The heterogeneous pancreatic CSC pool has been implicated in tumor propagation as well as metastatic spread. Clinically, the most important feature of CSCs is their strong resistance...

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PMID: 26202953
DOI: 10.1002/stem.2114

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