HLA-G*14 bp indel variant in autism spectrum disorder in a population from southern Brazil.

doi:10.1016/j.jneuroim.2023.578194

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Article

HLA-G*14 bp indel variant in autism spectrum disorder in a population from southern Brazil.

Journal of neuroimmunology - 15 Oct 2023

Ziliotto Marina, Kulmann-Leal Bruna, Kaminski Valéria de Lima, Nunes Guilherme Tyska, Riesgo Rudimar Dos Santos, Roman Tatiana, Schuch Jaqueline Bohrer, Chies José Artur Bogo

Abstract excerpt

Altered immune response during pregnancy has been associated with ASD susceptibility. HLA-G is expressed by the trophoblast at the maternal/fetal interface and induces allogenic tolerance toward the fetus. A 14-bp insertion in the HLA-G 3'UTR (rs371194629) was associated with reduced levels of HLA-G. We aimed to assess the influence of the HLA-G*14 bp indel variant in ASD susceptibility and symptomatology in a...

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PMID: 37683302
DOI: 10.1016/j.jneuroim.2023.578194

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