Article
HLA-class II haplotypes and Autism Spectrum Disorders.
Scientific reports - 16 May 2018
Bennabi Meriem, Gaman Alexandru, Delorme Richard, Boukouaci Wahid, Manier Céline, Scheid Isabelle, Si Mohammed Nassima, Bengoufa Djaouida, Charron Dominique, Krishnamoorthy Rajagopal, Leboyer Marion, Tamouza Ryad
Abstract excerpt
Infections and autoimmunity are associated with autism spectrum disorders (ASD), with both strongly influenced by the genetic regulation of the human leukocyte antigen (HLA) system. The relationship between ASD and the HLA genetic diversity requires further investigation. Using a case control design, the distribution of HLA class II-DRB1 and DQB1 alleles, genotypes and haplotypes were investigated in ASD...
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