Article
HLA-A, -B, -C and -DRB1 Association with Autism Spectrum Disorder Risk: A Sex-Related Analysis in Italian ASD Children and Their Siblings.
International journal of molecular sciences - 12 Sept 2024
Guerini Franca Rosa, Bolognesi Elisabetta, Mensi Martina Maria, Zanette Michela, Agliardi Cristina, Zanzottera Milena, Chiappedi Matteo, Annunziata Silvia, García-García Francisco, Cavallini Anna, Clerici Mario
Abstract excerpt
Autism Spectrum disorders (ASD) are diagnosed more often in males than in females, by a ratio of about 3:1; this is likely to be due to a difference in risk burden between the sexes and/or to "compensatory skills" in females, that may delay the diagnosis of ASD. Identifying specific risk factors for ASD in females may be important in facilitating early diagnosis. We investigated whether HLA- class I: -A, -B, -C...
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