Article
An HLA-G(∗)14bp insertion/deletion polymorphism associates with the development of autistic spectrum disorders.
Brain, behavior, and immunity - 1 Feb 2015
Guerini Franca R, Bolognesi Elisabetta, Chiappedi Matteo, Ghezzo Alessandro, Canevini Maria Paola, Mensi Martina M, Vignoli Aglaia, Agliardi Cristina, Zanette Michela, Clerici Mario
Abstract excerpt
HLA-G expressed by the trophoblast ligates KIR molecules expressed by maternal NK cells at the uterine fetal/maternal interface: this interaction is involved in generating immune tolerance during pregnancy. A 14-bp insertion in the HLA-G 3'-UTR associates with significantly reduced levels of both...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
