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Article

Causal relationship between sex hormone-binding globulin and major depression: A Mendelian randomization study.

Acta psychiatrica Scandinavica - 1 Nov 2023

Zhu Haohao, Sun Yifan, Guo Shuaiyi, Zhou Qin, Jiang Ying, Shen Yuan, Zhou Zhenhe, Du Zhiqiang, Zhou Hongliang

Abstract excerpt

OBJECTIVE: This study aimed to explore the causal relationship between sex hormone-binding globulin (SHBG) and major depression using two-sample Mendelian randomization (MR) studies. METHODS: Based on the genome-wide association study (GWAS) summary data of SHBG and major depression in the European population, which included 214,989 female SHBG samples, 185,221 male SHBG samples, and 500,199 major depression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37681458
DOI: 10.1111/acps.13614

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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