Mendelian randomization study on the causal link between reproductive behavior and postpartum depression.

Abstract excerpt

This study employed Mendelian randomization (MR) to explore the causal relationships between age at first sexual intercourse (AFS), lifetime number of sexual partners (LNSP), age at first birth (AFB) and risk of postpartum depression (PPD). We used aggregated data from genome-wide association studies to analyze AFS, LNSP, and AFB as exposure variables, with PPD as the outcome variable. Single nucleotide...

Topics

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• Depression, Postpartum
• Genome-Wide Association Study
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide
• Risk Factors