Article
The causal relationship of female infertility and psychiatric disorders in the European population: a bidirectional two-sample Mendelian randomization study.
BMC women's health - 19 Jan 2024
Zeng Pengfei, Zhang Hanxiao, Lu Liyue, Li Yanting, Yu Tong, Zhang Jun, Zhou Hang
Abstract excerpt
BACKGROUND: Infertility affects many couples globally, causing physical, emotional, and financial burdens. While observational studies suggest a link between psychiatric disorders and female infertility, causal relationships remain uncertain. Mendelian randomization analysis, using genome-wide association studies data, minimizes confounding factors and reverse causation, providing valuable insights into causal...
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