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Causal relationship between schizophrenia and sex hormone binding globulin: A Mendelian randomization study.

Schizophrenia research - 1 May 2024

Ou Mengmeng, Du Zhiqiang, Jiang Ying, Zhou Qin, Yuan Jianming, Tian Lin, Zhu Haohao

Abstract excerpt

OBJECTIVE: The underlying etiology of schizophrenia is still not fully understood, and recent studies have pointed to a potential link between hormonal factors and the risk of developing this condition. Sex Hormone-Binding Globulin (SHBG) is a protein that regulates the bioavailability of sex hormones. However, the causal relationship between SHBG levels and schizophrenia remains unclear, this study aimed to...

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PMID: 37735050
DOI: 10.1016/j.schres.2023.09.030

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