Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain tumour genetic network signatures of survival.

Brain : a journal of neurology - 2 Nov 2023

Ruffle James K, Mohinta Samia, Pombo Guilherme, Gray Robert, Kopanitsa Valeriya, Lee Faith, Brandner Sebastian, Hyare Harpreet, Nachev Parashkev

Abstract excerpt

Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterized by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions across multiple molecular pathways. Predicting disease evolution and prescribing individually optimal treatment requires statistical models complex enough to capture the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Bioinformatics and Genomic Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to Gene Regulatory Networks

Share to Glioma

Share to Glioma Diagnosis and Treatment

Share to Isocitrate Dehydrogenase

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 37665980
DOI: 10.1093/brain/awad199
PMCID: PMC10629773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain tumour genetic network signatures of survival.PMID 37665980Read ↗

Genetic evolution and cellular interactions within the tumour microenvironment determine glioblastoma progressionSemantic proximity Read ↗

Multi-omics integrative analysis of the glioma microenvironment reveals IDH-dependent cellular communication and prognostic signaturesSemantic proximity Read ↗

Integrating gene mutation spectra from tumors and the general population with gene expression topological networks to identify novel cancer driver genesSemantic proximity Read ↗

Multi-faceted computational assessment of risk and progression in oligodendroglioma implicates NOTCH and PI3K pathwaysSemantic proximity Read ↗

Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by gliomaSemantic proximity Read ↗

DeepGliomaAI: A Variational Autoencoder Framework for Interpretable Transcriptomic Representation and Prognostic Stratification in GliomaSemantic proximity Read ↗

Tumor radiogenomics in gliomas with Bayesian layered variable selection.Semantic proximity Read ↗

H3K4-H3K9 Histone Methylation Patterns and Oncofetal Developmental Networks as Drivers of Cell Fate Decisions in Pediatric High-Grade GliomasSemantic proximity Read ↗

Identifying predictors of glioma evolution from longitudinal sequencing.Semantic proximity Read ↗

Lesion covariance networks reveal proposed origins and pathways of diffuse gliomasSemantic proximity Read ↗

An atlas of causal and mechanistic drivers of interpatient heterogeneity in gliomaSemantic proximity Read ↗

Transcriptomic and connectomic correlates of differential spatial patterning among glioblastomas and low-grade gliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.