Article

Lesion covariance networks reveal proposed origins and pathways of diffuse gliomas

2021-04-13

Abstract excerpt

Diffuse gliomas have been hypothesized to originate from neural stem cells in the subventricular zone. Here, we evaluated this hypothesis by mapping independent sources of glioma localization and determining their relationships with neurogenic niches, genetic markers, and large-scale connectivity networks. Using lesion data from a total of 410 patients with glioma, we identified -- and replicated in an independent...

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Literature Corpus work: e9a0beca-1e7a-504b-9734-96b4ea758dc0
DOI: 10.1101/2021.04.09.21255209

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