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Multi-faceted computational assessment of risk and progression in oligodendroglioma implicates NOTCH and PI3K pathways

18 Oct 2018

Abstract excerpt

-mutation and co-deletion of 1p/19q. They have highly variable clinical courses, with survivals ranging from 6 months to over 20 years, but little is known regarding the pathways involved with their progression or optimal markers for stratifying risk. We utilized machine-learning approaches with genomic data from The Cancer Genome Atlas to objectively identify molecular factors associated with clinical outcomes...

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PMID: 30417117
DOI: 10.1038/s41698-018-0067-9

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