Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patients with telomere biology disorders show context specific somatic mosaic states with high frequency of U2AF1 variants

4 Sept 2023

Abstract excerpt

Somatic mosaic states in telomere biology disorders are characterized by somatic variants in the spliceosome and DNA damage response and repair pathways. A likely maladaptive response to short telomeres that may lead to increased hematological cancer.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Renal and related cancers
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37665761
DOI: 10.1002/ajh.27086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patients with telomere biology disorders show context specific somatic mosaic states with high frequency of U2AF1 variantsPMID 37665761Read ↗

Clinical and molecular spectrum and prognostic outcomes of U2AF1 mutant clonal hematopoiesis- a prospective mayo clinic cohort study.Semantic proximity Read ↗

<i>U2AF1</i> mutations alter splice site recognition in hematological malignanciesSemantic proximity Read ↗

U2AF1 mutations alter splice site recognition in hematological malignancies.Semantic proximity Read ↗

Different phenotypes with different endings—Telomere biology disorders and cancer predisposition with long telomeresSemantic proximity Read ↗

Clonal hematopoiesis in telomere biology disorders.Semantic proximity Read ↗

Clonal Signatures of Telomere Biology Disorders.Semantic proximity Read ↗

Genetic drivers and clinical consequences of mosaic chromosomal alterations in 1 million individualsSemantic proximity Read ↗

Somatic Mosaicism in Biology and Disease.Semantic proximity Read ↗

Genetics of human telomere biology disordersSemantic proximity Read ↗

Fanconi anemia and dyskeratosis congenita/telomere biology disorders: Two inherited bone marrow failure syndromes with genomic instabilitySemantic proximity Read ↗

Splicing dysregulation in human hematologic malignancies: beyond splicing mutations.Semantic proximity Read ↗

Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.