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Article

Do environmental factors modify the genetic risk of prostate cancer?

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2015

Loeb Stacy, Peskoe Sarah B, Joshu Corinne E, Huang Wen-Yi, Hayes Richard B, Carter H Ballentine, Isaacs William B, Platz Elizabeth A

Abstract excerpt

BACKGROUND: Many SNPs influence prostate cancer risk. To what extent genetic risk can be reduced by environmental factors is unknown. METHODS: We evaluated effect modification by environmental factors of the association between susceptibility SNPs and prostate cancer in 1,230 incident prostate cancer cases and 1,361 controls, all white and similar ages, nested in the Prostate, Lung, Colorectal, and Ovarian (PLCO)...

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PMID: 25342390
DOI: 10.1158/1055-9965.EPI-14-0786-T
PMCID: PMC4337874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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