Article
Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese.
Stroke and vascular neurology - 27 Aug 2024
Yang Songchun, Sun Zhijia, Sun Dong, Yu Canqing, Guo Yu, Sun Dianjianyi, Pang Yuanjie, Pei Pei, Yang Ling, Millwood Iona Y, Walters Robin G, Chen Yiping, Du Huaidong, Lu Yan, Burgess Sushila, Avery Daniel, Clarke Robert, Chen Junshi, Chen Zhengming, Li Liming, Lv Jun
Abstract excerpt
BACKGROUND AND PURPOSE: Previous studies, mostly focusing on the European population, have reported polygenic risk scores (PRSs) might achieve risk stratification of stroke. We aimed to examine the association strengths of PRSs with risks of stroke and its subtypes in the Chinese population. METHODS: Participants with genome-wide genotypic data in China Kadoorie Biobank were split into a potential training set...
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