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Article

Germline CDH1 variants in hereditary diffuse gastric cancer syndrome with focus on younger women.

Journal of cancer research and clinical oncology - 1 Nov 2023

Corso Giovanni, Comelli Giovanni, Veronesi Paolo, Bianchi Beatrice, Petitto Salvatore, Polizzi Andrea, Girardi Antonia, Cioffi Antonio, La Vecchia Carlo, Bagnardi Vincenzo, Magnoni Francesca

Abstract excerpt

PURPOSE: The objective of this study was to determine the male and female frequency of diffuse gastric cancer (DGC), the age at diagnosis, and the country of origin in a selected population with germline CDH1 variants from families with the hereditary diffuse gastric cancer (HDGC) syndrome. METHODS: Relevant literature dating from 1998 to 2021 was systematically searched for data on CDH1 gene. The Wilcoxon rank...

Topics

Humans
Male
Female
Infant
Stomach Neoplasms
Pedigree
Genetic Testing
Adenocarcinoma
Germ Cells
Cadherins
Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Antigens, CD

Source

Identifiers

PMID: 37639007
DOI: 10.1007/s00432-023-05318-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-37639007-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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