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Tau Loss of Function, by Deletion or Aggregation, Contributes to Peripheral Insulin Resistance

22 Aug 2023

Abstract excerpt

BACKGROUND: Several epidemiological data revealed an association between Alzheimer's disease (AD) and type 2 diabetes. Researchers concentrated on brain insulin resistance with little emphasis on the link between systemic insulin resistance and AD, despite the fact that the incidence of type 2 diabetes is higher in AD patients and that impairment in insulin signaling is a risk factor for AD. OBJECTIVE: The goal...

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PMID: 37638441
DOI: 10.3233/jad-230392

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