Article
Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature.
European journal of internal medicine - 1 Oct 2012
Vardi Moshe, Blum Shany, Levy Andrew P
Abstract excerpt
BACKGROUND: Diabetes mellitus carries a high risk for vascular events. Diabetics with different haptoglobin (Hp) types may carry different risk profiles, and may respond differently to vitamin E treatment. We aim to summarize the evidence about cardiovascular risk in diabetic patients, according to their Hp type, and the effect of vitamin E treatment on these sub-groups. METHODS: We searched MEDLINE and on-going...
Topics
- Antioxidants
- Cardiovascular Diseases
- Diabetes Complications
- Diabetes Mellitus
- Genotype
- Haptoglobins
- Humans
- Myocardial Infarction
- Pharmacogenetics
- Risk Factors
- Stroke
- Vitamin E