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Targeting cellular senescence: A promising approach in respiratory diseases

21 Aug 2023

Abstract excerpt

Cellular senescence serves as a significant tumor suppression mechanism in mammals. Cellular senescence is induced in response to various stressors and acts as a safeguard against the uncontrolled proliferation of damaged cells that could lead to malignant transformation. Senescent cells also exhibit a distinctive feature known as the senescence-associated secretory phenotype (SASP), wherein they secrete a range...

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PMID: 37604771
DOI: 10.1111/ggi.14653

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