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Article

Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease.

European heart journal - 1 Aug 2010

Brugts Jasper Jan, Isaacs Aaron, Boersma Eric, van Duijn Cock M, Uitterlinden Andre G, Remme Willem, Bertrand Michel, Ninomiya Toshiharu, Ceconi Claudio, Chalmers John, MacMahon Stephen, Fox Kim, Ferrari Roberto, Witteman Jacqueline C M, Danser A H Jan, Simoons Maarten L, de Maat Moniek P M

Abstract excerpt

AIMS: The efficacy of angiotensin-converting enzyme (ACE)-inhibitors in stable coronary artery disease (CAD) may be increased by targeting the therapy to those patients most likely to benefit. However, these patients cannot be identified by clinical characteristics. We developed a genetic profile...

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Source

Identifiers

PMID: 20538738
DOI: 10.1093/eurheartj/ehq169

Genes

ACE
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20538738-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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