Peripheral T cell populations are differentially affected in monogenic autoinflammatory syndromes and gout

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose </bold>Both monogenic autoinflammatory syndromes, such as Chronic Granulomatous Disease (CGD) and Familial Mediterranean Fever (FMF), and the common inflammatory disease gout are characterized by episodes of sterile inflammatory attacks in the absence of an infection. While these disorders encompass distinct pathologies due to differentially affected metabolic pathways and...

Topics

Open a Topic to create a Post that cites this publication.

• Autoimmune Diseases
• Immunity, Innate
• Inflammasomes
• Inflammation
• Interferons
• Interleukin-1
• NF-kappa B
• Tumor Necrosis Factor-alpha

Identifiers and source

Literature Corpus work

0ed7269a-1d6e-5c48-afea-687094518bd4

DOI

10.21203/rs.3.rs-2421679/v1