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Article

Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome.

Arthritis research & therapy - 11 Aug 2014

Vogelsang Petra, Karlsen Marie, Brun Johan G, Jonsson Roland, Appel Silke

Abstract excerpt

INTRODUCTION: Dendritic cells (DC) are the most potent antigen-presenting cells of the immune system, involved in both initiating immune responses and maintaining tolerance. Dysfunctional and via toll-like receptor (TLR) ligands activated DC have been implicated in the development of autoimmune diseases, but their role in the etiology of Sjögren's syndrome, a chronic inflammatory autoimmune disease characterized...

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Share to Dendritic Cells
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Real-Time Polymerase Chain Reaction

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Share to STAT1 Transcription Factor

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Source

Open in PubMed Open full text

Identifiers

PMID: 25113744
DOI: 10.1186/ar4682
PMCID: PMC4261979

Genes

TLR7
GAPDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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