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Article

CD8+ T Cells in GCA and GPA: Bystanders or Active Contributors?

Frontiers in immunology - 1 Jan 2021

Reitsema Rosanne D, Boots Annemieke M H, van der Geest Kornelis S M, Sandovici Maria, Heeringa Peter, Brouwer Elisabeth

Abstract excerpt

Vasculitis refers to inflammation of blood vessels and can cause a variety of serious complications depending on which vessels are affected. Two different forms of vasculitis are Giant Cell Arteritis (GCA) and Granulomatosis with Polyangiitis (GPA). GCA is the most common form of vasculitis in adults affecting the large arteries and can lead to visual impairment and development of aneurysms. GPA affects small-...

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Identifiers

PMID: 33815414
DOI: 10.3389/fimmu.2021.654109
PMCID: PMC8015776

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