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Article

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Molecular psychiatry - 1 Aug 2023

Nurmi E L, Laughlin C P, de Wit H, Palmer A A, MacKillop J, Cannon T D, Bilder R M, Congdon E, Sabb F W, Seaman L C, McElroy J J, Libowitz M R, Weafer J, Gray J, Dean A C, Hellemann G S, London E D

Abstract excerpt

Risky decision-making is a common, heritable endophenotype seen across many psychiatric disorders. Its underlying genetic architecture is incompletely explored. We examined behavior in the Balloon Analogue Risk Task (BART), which tests risky decision-making, in two independent samples of European ancestry. One sample (n = 1138) comprised healthy participants and some psychiatric patients (53 schizophrenia, 42...

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Identifiers

PMID: 37582857
DOI: 10.1038/s41380-023-02123-x
PMCID: PMC10618088

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