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[Analysis of BRAF and NRAS mutations in thyroid tumors in patients from Argentina].

Medicina - 1 Jan 2023

Repetto Esteban M, Fernandez Lucía, Lambertini Roberto, Del Valle Jaen Ana, Ruda Vega Verónica, Moldes Sofía, Lutfi Ruben, Aranda Claudio, Faure Eduardo, Oneto Adriana

Abstract excerpt

INTRODUCTION: Molecular alterations in follicular cells in the BRAF or NRAS genes have been reported to be associated with the process of carcinogenesis. Our aim was to determine the mutational frequency of BRAF and NRAS in fine-needle aspiration (FNA) specimens in our population. METHODS: The mutational status of BRAF (codon 600) and NRAS (codon 61) was analysed by qPCR in 193 FNA specimens from suspicious...

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PMID: 37582124

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