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Article

Relevance of BRAF and NRAS mutations in the primary tumor and metastases of papillary thyroid carcinomas.

Head & neck - 1 Dec 2016

Cañadas-Garre Marisa, Becerra-Massare Patricia, Moreno Casares Antonia, Calleja-Hernández Miguel Ángel, Llamas-Elvira José Manuel

Abstract excerpt

BACKGROUND: Multifocality of papillary thyroid carcinoma (PTC) is common. BRAF and NRAS mutations are the most frequent genetic alterations in PTC. The purpose of this study was to determine the distribution and relevance of BRAFT1799A and NRAS mutations in PTC. METHODS: BRAFT1799A and NRAS mutations were evaluated in 195 intrathyroid or metastatic foci from 29 patients with multifocal PTC. RESULTS: BRAFT1799A...

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Share to Carcinoma, Papillary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Share to Neoplasm Recurrence, Local

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 27299298
DOI: 10.1002/hed.24517

Genes

BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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