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Article

The variability of PNPLA3 gene as a potential marker of cold adaptation in Yakuts.

International journal of circumpolar health - 1 Dec 2023

Pavlova Nadezhda Ivanovna, Bochurov Alexey Alexeevich, Alekseev Vladislav Amirovich, Sydykova Lyubov Akhmedovna, Dodokhov Vladimir Vladimirovich, Kurtanov Khariton Alekseevich, Krylov Alexey Vasilievich

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. It has been reported that specific variants of patatin-like phospholipase domain-containing 3 (PNPLA3) gene, notably SNPs rs738409 and rs2294918 are associated with high risks of liver disease. PNPLA3 rs738409 polymorphism is the main determinant of fatty liver and affects development and progression of NAFLD. rs2294918 is...

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Share to Adipose Tissue and Metabolism
Share to Diet, Metabolism, and Disease
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Liver Disease Diagnosis and Treatment
Share to Non-alcoholic Fatty Liver Disease
Share to Phospholipases A2, Calcium-Independent
Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 37581274
DOI: 10.1080/22423982.2023.2246647
PMCID: PMC10431738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The variability of PNPLA3 gene as a potential marker of cold adaptation in Yakuts.PMID 37581274Read ↗

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