Article
High frequency of the PNPLA3 rs738409 [G] single-nucleotide polymorphism in Hmong individuals as a potential basis for a predisposition to chronic liver disease.
Cancer - 1 Apr 2018
Tepper Clifford G, Dang Julie H T, Stewart Susan L, Fang Dao M, Wong Kimberly A, Liu Stephenie Y, Davis Ryan R, Dao Doan Y, Gregg Jeffrey P, Török Natalie J, Chen Moon S
Abstract excerpt
BACKGROUND: An exploratory study was performed to determine the prevalence of the patatin-like phospholipase domain-containing protein 3 (PNPLA3) rs78409 [G] allele among the Hmong as a risk factor for nonalcoholic fatty liver disease (NAFLD). NAFLD/nonalcoholic steatohepatitis is the world's most common chronic liver disease and is expected to replace viral hepatitis as the leading cause of cirrhosis and...
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