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High Frequency of Ancestral Haplotype A of Fatty Acid Desaturase Genes in the Yakut Population.

Genetic testing and molecular biomarkers - 1 Aug 2024

Pavlova Nadezhda I, Krylov Alexey V, Bochurov Alexey A, Alekseev Vladislav A, Kurtanov Khariton A

Abstract excerpt

Aims: The purpose of this study was to study the correlation of the body weight of Yakuts with the variability of polymorphisms rs174537, rs174546 and rs3834458 of the FADS1 - FADS2 region to identify the connection of certain genotypes with obesity. Materials and Methods: For genotyping, classical methods of PCR-RFLP analysis were used. A sample of 446 DNA samples from Yakut volunteers without chronic diseases...

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PMID: 38860387
DOI: 10.1089/gtmb.2024.0085

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