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Article

Manganese level and cognitive decline in older adults with the APOE e4 allele: a preliminary study.

Psychiatry research - 1 Sept 2023

Kim Shin Gyeom, Choe Young Min, Suh Guk-Hee, Lee Boung Chul, Choi Ihn-Geun, Kim Hyun Soo, Hwang Jaeuk, Keum Mu-Sung, Yi Dahyun, Kim Jee Wook

Abstract excerpt

This study examined the relationship between serum manganese level and cognition, and the moderating effect of apolipoprotein E ε4 (APOE4) on this relationship. A total of 164 non-demented participants underwent clinical assessments including serum manganese level and cognition [episodic memory score (EMS), non-memory score (NMS) for executive function/attention/language/ visuospatial skill, and total score...

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PMID: 37579537
DOI: 10.1016/j.psychres.2023.115403

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