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Triple-recognition strategy for one-pot detection of single nucleotide variants by aligner-mediated cleavage-triggered exponential amplification.

Analytica chimica acta - 2 Oct 2023

Long Jinyan, Chen Mengqi, Yu Yang, Wu Qiaomin, Yang Xiaolan

Abstract excerpt

The detection of single nucleotide variants (SNVs) is important for the diagnosis and treatment of cancer. To date, researchers have devised several methods to detect SNVs, but most of them are complex and time-consuming. To improve SNVs detection specificity and sensitivity, we developed a triple-recognition strategy, which facilitates aligner-mediated cleavage-triggered exponential amplification...

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Class I Phosphatidylinositol 3-Kinases
ErbB Receptors
EGFR gene
Nucleic Acid Amplification Techniques
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37573107
DOI: 10.1016/j.aca.2023.341617

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EGFR

Variants

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