Article
Relationship between biotransformation enzyme genes in polycyclic aromatic hydrocarbon metabolism, telomere length and missed abortion.
International journal of environmental health research - 1 May 2026
Wang Yujia, Zhang Jiayu, Chang Kewei, Liu Sha, Ji Jingru, Han Mei, Wei Junni
Abstract excerpt
The mechanism underlying the effects of Polycyclic aromatic hydrocarbons (PAHs) on missed abortion (MA) remains unclear. This study explored the relationship between PAHs exposure, telomere length (TL), metabolizing enzyme gene polymorphism, and MA in a case-control study with 253 pregnant women. A competitive enzyme-linked immunosorbent assay (ELISA) was used to quantify PAH-DNA adducts. The DNA was extracted...
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