Article
Elevated circulating CD19+CD24hiCD38hi B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy.
Immunology letters - 1 Sept 2023
Deng Bishun, Deng Li, Liu Miao, Zhao Ziling, Huang Huijie, Tu Xiaoxin, Liang Enyu, Tian Ruimin, Wang Xiaowan, Wang Rongrong, Lin Haibiao, Yu Yongyi, Peng Anping, Xu Peng, Bao Kun, He Min
Abstract excerpt
CD19+CD24hiCD38hi regulatory B cells exert immunosuppressive functions by producing IL-10, but their role in idiopathic membranous nephropathy (IMN) remains elusive. Here, we investigated the frequency and functional changes of circulating CD19+CD24hiCD38hi B cells and evaluated the correlation of CD19+CD24hiCD38hi B cells with clinical features and T helper cell subsets in IMN patients. Compared with healthy...
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