HSP70, a Novel Regulatory Molecule in B Cell-Mediated Suppression of Autoimmune Diseases

Abstract excerpt

B cells have recently emerged as playing regulatory role in autoimmune diseases. We have previously demonstrated that human peripheral blood CD19+ CD24hiCD27+ B cells have regulatory function both in healthy donors and in patients with autoimmune disease. However, the mechanism of this regulation is still not fully understood. In this study, microarrays were utilized to compare gene expression of CD19+...

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